My dog is on trefexius and doing well. With saying that I was told that the heart worm pill inside of it is heart guard. He also stays inside every night and when someone is home during the day. I have a alarm set on my phone to make sure he gets it every month on the same day and as close as possible to the same time. If I remember correct, I don't think pro heart has any resistance to ticks but I could be wrong. It's been a while since I did research on it.
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