First time exposure develops antibodies... which in turn produce mild reactions that she may never have attributed to the shellfish (sneeze, runny nose,) which are common when people consume spicy foods... after a prolonged period of exposure it could trigger more severe reactions (true anaphylaxis i.e. wheezing, swelling, itching, etc.) or hypersensitivity. Thats just my theory. there are several explanations on sensitization and exposure.
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