all about shot placement. you hit a deer in the heart head or neck with any one of those calibers and its not going far. ive drop shot a few deer with a heart shot and they fall just like a head shot. some i have hit square in the heart and still run about 15 yards. bullets make a difference also. if you shot a ballistic tip all the energy of the bullet is released on impact pretty much knocking the deer down will a tight mushroom bullet passes through not releasing all of its power just penetrating more.
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