The most effective caliber is the one you can shoot accurately. You wouldn't give your 7 year old a 10 gauge to take teal hunting and expect him to drop em every shot. No, because he can't accurately handle that size weapon. If you can shoot a great pattern and double tap a .45 accurately, then that's your caliber. If you can't then try .40. Still can't? Try 9mm. Still can't? Try .380. I'd rather be missed by .50 cal than hit by a .22. Debate over.
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